Motor and cognitive outcomes in nondisabled low-birth-weight adolescents: early determinants.

نویسندگان

  • Agnes H Whitaker
  • Judith F Feldman
  • John M Lorenz
  • Sa Shen
  • Fiona McNicholas
  • Marlon Nieto
  • Dawn McCulloch
  • Jennifer A Pinto-Martin
  • Nigel Paneth
چکیده

OBJECTIVES To describe motor and cognitive outcomes in nondisabled low-birth-weight (LBW) adolescents and to determine the relation of specific prenatal, perinatal, and neonatal risk factors to these outcomes. DESIGN A prospective epidemiological study. SETTING An adolescent follow-up of a regional LBW (<2000 g) cohort born in or admitted to 3 hospitals between September 1, 1984, and June 30, 1987 (n = 1105). Of 862 eligible survivors, 628 (72.9%) underwent assessment at a mean age of 16 years; of these, 33 had severe disability that precluded psychometric evaluation. The 474 nondisabled adolescents undergoing assessment at home had slightly less social risk at birth than did all other nondisabled eligible adolescents. PARTICIPANTS The 474 nondisabled LBW adolescents assessed at home. Main Exposures Basic birth characteristics (social risk, sex, fetal growth ratio, and gestational age), neonatal cranial ultrasound abnormalities, and other early medical complications. MAIN OUTCOME MEASURES Riley Motor Problems Inventory and Wechsler Abbreviated Scales of Intelligence. RESULTS Nondisabled LBW adolescents had an excess of motor problems compared with the normative sample. The IQ scores, although within the normal range, were significantly lower than population norms. Independent predictors of total motor problems included male sex, white matter injury on neonatal ultrasound, and days of ventilation. Independent predictors of lower Full Scale IQ scores included social disadvantage, fetal growth ratio, and white matter injury on neonatal ultrasound. CONCLUSIONS Specific prenatal, perinatal, and neonatal risk factors influence motor and cognitive performance in nondisabled LBW survivors well into adolescence, even when controlling for social risk. Advances in maternal-fetal and neonatal care can substantially improve these long-term outcomes.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of motor development of low birth weight (LBW) infants with and without using mechanical ventilation and normal birth weight infants

Background: To determine whether using mechanical ventilation in neonatal intensive care unit (NICU) influences motor development of low birth weight (LBW) infants and to compare their motor development with normal birth weight (NBW) infants at the age of 8 to 12 months using Peabody Developmental Motor Scale 2 (PDMS-2). Methods: This cross sectional study was conducted on 70 LBW infants in ...

متن کامل

COMPARISON OF ANTHROPOMETRIC INDICATORS, IQ, AND MOTOR DEVELOPMENT IN PRESCHOOL CHILDREN WITH AND WITHOUT LOW BIRTH WEIGHT

Background & Aims: Birth weight is an important indicator of child health that affects various aspects of physical and cognitive development. This study aimed to compare the anthropometric indicators, IQ, and motor development in preschool children with and without low birth weight. Materials & Methods: The type of this research is comparative.The population consisted of preschool children in ...

متن کامل

Segmental brain volumes and cognitive and perceptual correlates in 15-year-old adolescents with low birth weight.

OBJECTIVE To determine whether preterm very low birth weight (VLBW) or term born small for gestational age (SGA) adolescents have reduced regional brain volumes. We also asked which perinatal factors are related to reduced brain volume in VLBW adolescents, which regional brain volumes are associated with cognitive and perceptual functioning, and if these differ between the groups. STUDY DESIG...

متن کامل

Effects of socioeconomic status on motor proficiency of 4-6 years old Tehran children with very low and normal birth weight

This study aimed to evaluate the direct and interactive effects of socioeconomic status and birth weight on Tehran children motor proficiency. : The present study was a cross-sectional research which conducted in April and May of 2016 and the study population included 4/5 to 6-year-old boys and girls with very low and normal birth weight from 2 and 19 districts of Tehran city that from which 13...

متن کامل

پیامد تکاملی نوزادان نارس و کم‌وزن: مروری بر شواهد موجود

Low birth weight (LBW) and preterm birth are one the most important causes of death in the world and therefore are considered as one of the major health problems. Global statistics demonstrates an increase in the prevalence of low birth weight in the developing countries. Low birth weight infants are exposed to complications such as major neurosensory impairements, cerebral palsy, cognitive and...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Archives of pediatrics & adolescent medicine

دوره 160 10  شماره 

صفحات  -

تاریخ انتشار 2006